Telescoped Synthesis of 2-Acyl-1-aryl-1,2-dihydroisoquinolines and Their Inhibition of the Transcription Factor NF-κB

DOI: 10.1021/acscombsci.5b00001

Source and publish data:

ACS Combinatorial Science p. 442 - 451 (2015)

Update date:2022-07-29

Topics:

Authors:

Chung, Tsai-Wen

Hung, Yi-Tzu

Thikekar, Tushar

Paike, Vijaykumar V.

Lo, Fu Yuan

Tsai, Pei-Hua

Liang, Mei-Chih

Sun, Chung-Ming

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Article abstract of DOI:10.1021/acscombsci.5b00001

(Chemical Equation Presented). A sequential single-flask multicomponent reactions is highly effective for the synthesis of 1,2-dihydroisoquinolines through amidealkylation from intermediate N-acylisoquinolinium salts under mild conditions. N-Acylisoquinol

Full text of DOI:10.1021/acscombsci.5b00001

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