Journal of Organic Chemistry p. 2982 - 2987 (1982)
Update date:2022-07-30
Topics:
Pastuszak, Jacek
Gardner, Joseph H.
Singh, Jasbir
Rich, Daniel H.
A complete search for the optimal conditions for preparing cycling tetrapeptide 2 was carried out.In this study all four possible sequences of the linear tetrapeptide precursors were synthesized and cyclized.The results establish that one linear sequence is especially favorable for synthesizing the peptide ring system in chlamydocin (1).
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