6- And 1- substituted mannosyl phosphotriesters as lipophilic macrophage-targeted carriers of antiviral nucleosides

DOI: 10.1016/S0040-4039(01)93843-2

Source and publish data:

Tetrahedron Letters p. 6019 - 6022 (1989)

Update date:2022-07-30

Topics:

Authors:

Gouyette

Neumann Neumann

Fauve Fauve

Huynh-Dinh

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Article abstract of DOI:10.1016/S0040-4039(01)93843-2

Lipophilic mannose-6 phosphate and (1-α mannosyl)ethyl phosphate derivatives of the antiviral nucleosides 3'-azido thymidine (AZT), 2',3'-dideoxy thymidine (ddT) and 2'-deoxy 5-fluoro uridine (dU(F)) were prepared from D-mannose as membrane soluble prodru

Full text of DOI:10.1016/S0040-4039(01)93843-2

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