Variation in the aromatic ring of cromakalim: Antihypertensive activity of pyranopyridines and 6-alkyl-2H-1-benzopyrans

DOI: 10.1021/jm00173a018

Source and publish data:

Journal of Medicinal Chemistry p. 3023 - 3027 (1990)

Update date:2022-08-04

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Authors:

Burrell Burrell

Cassidy Cassidy

Evans Evans

Lightowler

Stemp Stemp

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Article abstract of DOI:10.1021/jm00173a018

The synthesis and antihypertensive activity in the spontaneously hypertensive rat of two new series of analogues related to cromakalim (1) are described. In the first series, where the benzopyran nucleus has been replaced by a pyranopyridine nucleus, the

Full text of DOI:10.1021/jm00173a018

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