ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE CYCLOHEXENOL DERIVATIVES VIA HIGHLY STEREOSELECTIVE REDUCTION OF (R)-3-(p-t-BUTYLPHENYLTHIO)CYCLOHEXAN-1-ONE

Article abstract of DOI:10.1246/cl.1982.899

(R)-3-(p-t-Butylphenylthio)cyclohexan-1-one was reduced with LiAlH(OBu^t)3 to afford (1S,3R)-3-(p-t-butylphenylthio)cyclohexan-1-ol, while the same reduction with LiBH(s-Bu)3 afforded the (1R,3R) counterpart almost exclusively.Elaboration of eac