The antihypertensive and positive inotropic diterpene forskolin: Effects of structural modifications on its activity

DOI: 10.1021/jm00358a006

Source and publish data:

Journal of Medicinal Chemistry p. 486 - 492 (1983)

Update date:2022-09-26

Topics:

Authors:

Bhat Bhat

Dohadwalla

Bajwa Bajwa

Dadkar Dadkar

Dornauer

de Souza

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Article abstract of DOI:10.1021/jm00358a006

Four naturally occurring analogues of forskolin were isolated. Forty-nine semisynthetic derivatives were prepared, incorporating structural alterations at the 1-, 6-, 7-, 9-, 11-, and 14/15-positions. Blood pressure lowering properties of 53 compounds wer

Full text of DOI:10.1021/jm00358a006

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