The antihypertensive and positive inotropic diterpene forskolin: Effects of structural modifications on its activity

DOI: 10.1021/jm00358a006

Source and publish data:

Journal of Medicinal Chemistry p. 486 - 492 (1983)

Update date:2022-09-26

Topics:

Authors:

Bhat Bhat

Dohadwalla

Bajwa Bajwa

Dadkar Dadkar

Dornauer

de Souza

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00358a006

Four naturally occurring analogues of forskolin were isolated. Forty-nine semisynthetic derivatives were prepared, incorporating structural alterations at the 1-, 6-, 7-, 9-, 11-, and 14/15-positions. Blood pressure lowering properties of 53 compounds wer

Full text of DOI:10.1021/jm00358a006

Products guided by the article

Product name:C₃₄H₄₂N₂O₈

Cas No:84048-22-6

R&D Labs maybe for 84048-22-6

henan victory industry co.ltd

Contact:86-371-63655023

Address:No.85,jinshui road,zhengzhou,China
Suzhou SuKaiLu Chemical Technology Co., Ltd.

Contact:+86-512-62766020

Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Chengdu Pukang Biotechnology Co., Ltd

Contact:+86-28-82550498

Address:No. 558 Rulin Road,Xinjin county,Chengdu city, China
Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China

Relevant to this article

Acid-catalyzed Ethanolysis of Di-1-azulenyl Ketones

Doi:10.1016/S0040-4039(00)73636-7
(1993)
Study of the reactivity of palladacycles containing [C(sp², ferrocene),N,S]^- or [C(sp³),N,S]^- terdentate ligands with symmetric alkynes

Doi:10.1016/j.jorganchem.2004.09.017
(2005)
Phthalocyanines and Tetrapyrazinoporphyrazines with Two Cationic Donuts: High Photodynamic Activity as a Result of Rigid Spatial Arrangement of Peripheral Substituents

Doi:10.1021/acs.jmedchem.7b00272
(2017)
Synthesis, radiosynthesis and preliminary in vivo evaluation of [ ¹²³I]-(4-fluorophenyl) {1-[2-(2-iodophenyl)ethyl]piperidin-4-yl} methanone, a potential 5-HT_2A-antagonist for SPECT brain imaging

Doi:10.1002/jlcr.845
(2004)
Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard

Doi:10.1021/jm00359a003
(1983)
Synthesis and antitumor activity of novel 1-(2′-alkyl(or phenyl)thioethoxy)methyl-5-fluorouracils and their oxidation products

Doi:10.1002/hc.20059
(2004)

Article Doi