Design, synthesis and pharmacokinetic evaluation of a novel series of triazole-based Src kinase inhibitors with anti-proliferative activity

Article abstract of DOI:10.2174/157018011793663930

Src has been recognized as an important therapeutic target for the treatment of cancer. A novel series of triazole-based Src inhibitors were synthesized and evaluated for their anti-proliferative activities in vitro against human lung cancer A549 cells wi