Journal of the Chemical Society. Chemical communications p. 1282 - 1283 (1982)
Update date:2022-08-03
Topics:
Soai, Kenso
Komiya, Kazuyuki
Shigematsu, Yasuhiko
Hasegawa, Hitoshi
Ookawa, Atsuhiro
The mixed solvent tetrahydrofuran + methanol (99 : 1) was much more effective than the individual solvents in the asymmetric reduction of chiral α-keto-amides with sodium borohydride; this solvent effect in asymmetric induction is unprecedented.
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