The first total synthesis of kwakhurin, a characteristic component of a rejuvenating plant, "kwao keur": Toward an efficient synthetic route to phytoestrogenic isoflavones

DOI: 10.1039/b414955f

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Organic and Biomolecular Chemistry p. 674 - 681 (2005)

Update date:2022-09-26

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Authors:

Ito, Fumihiro

Iwasaki, Misako

Watanabe, Toshiko

Ishikawa, Tsutomu

Higuchi, Yoshihiro

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Article abstract of DOI:10.1039/b414955f

A convergent synthesis of kwakhurin (5), a characteristic estrogen-like isoflavone of Pueraria mirifica (Leguminosae), is described. Isoflavone skeleton 31 was constructed by Suzuki-Miyaura coupling of 3-bromochromone 26 (AC-ring) and arylboronic acid 30

Full text of DOI:10.1039/b414955f

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