New Chiral Stationary Phases with Two Chiral Centers for the Liquid Chromatographic Resolution of Racemic Anti-inflammatory Drugs Related to α-Arylpropionic Acids

DOI: 10.1246/cl.1994.1021

Source and publish data:

Chemistry Letters p. 1021 - 1024 (1994)

Update date:2022-08-03

Topics:

Authors:

Hyun, Myung Ho

Hwang, Seung-Ryul

Ryoo, Jae-Jeong

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Article abstract of DOI:10.1246/cl.1994.1021

New chiral stationary phases (CSPs) with two chiral centers were prepared from (R)- or (S)-α-naphthylethylamine and (S)-naproxen.The (R,S)-CSP prepared from (R)-α-naphthylethylamine and (S)-naproxen was found to be very successful in resolving 3,5-dinitroanilide derivatives of antiinflammatory drugs related to α-arylpropionic acids.

Full text of DOI:10.1246/cl.1994.1021

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