Stereochemistry of hexenyl radical cyclizations with tert-butyl and related large groups: Substituent and temperature effects

Article abstract of DOI:10.1021/ja042595u

The long held notion that hexenyl radicals bearing large substituents on the radical carbon cyclize to give 1,2-trans-substituted cyclopentanes is experimentally disproved by study of the radical cyclization of an assortment of simple and complex substrat