
Chemistry Letters p. 1951 - 1952 (1982)
Update date:2022-07-29
Topics:
Masuyama, Yoshiro
Usukura, Masa-aki
Kurusu, Yasuhiko
The reaction of 1,2-diols with dimethyl sulfoxide-catalytic molybdenum peroxide in refluxing toluene generally resulted in monoprotection of diols to give 2-methylthiomethoxy-1-ols (Course A).Exceptionally, a) cis-1,2-cyclooctanediol and benzopinacol, and b) 1,2-cyclododecanediol caused C-C bond cleavage (Course B) and monooxidation (Course C), respectively as Scheme 1.
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