Design, synthesis and antiviral activity of novel 4,5-disubstituted 7-(β-D-ribofuranosyl)pyrrolo[2,3-d][1,2,3]triazines and the novel 3-amino-5-methyl-1-(β-d-ribofuranosyl)- and 3-amino-5-methyl-1-(2-deoxy- β-d-ribofuranosyl)-1,5-dihydro-1,4,5,6,7,8-hexaa

Article abstract of DOI:10.1021/jm0402014

The synthesis of several heterocyclic analogues of the biologically important nucleoside antibiotic toyocamycin and the tricyclic nucleoside triciribine (TCN) were prepared along with their 2′-deoxy counterparts. Coupling of 2-nitropyrrole-3,4-dicarboxami