Acid Catalyzed Condensation of Isoprene with Orcinol: Synthesis of 2,2-Dimethylchromans and 5-Methylxanthyletin Derivatives

Article abstract of DOI:10.1007/BF00809377

Condensation of orcinol with 2-methylbuta-1,3-diene (isoprene) has been achieved in the presence of orthophosphoric acid as catalyst leading to the exclusive formation of 2,2-dimethylchromans in one step.A novel route for the synthesis of 5-methylxanthyletin derivatives is described. - Keywords: 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; 2,2-Dimethylchromans; 2-Methylbuta-1,3-diene; 5-Methylxanthyletin; Orcinol; Pechmann condensation