STUDIES ON STRUCTURALLY SIMPLE α,β-BUTENOLIDES-II (-)-(S)-γ-HYDROXYMETHYL-α,β-BUTENOLIDE AND DERIVATIVES FROM D-RIBONOLACTONE EFFICIENT SYNTHESIS OF (-)-RANUNCULIN

Article abstract of DOI:10.1016/0040-4020(82)87017-8

A short synthesis of the title compound, 16, from D-ribonolactone is described.Two alternative approaches differing in the timing of the C=C double bond creation are used to prepare some chiral derivatives of 16. (-)-Ranunculin, a glycoside present in Ranunculaceae, has been synthetized for the first time.