Synthesis and pharmacological characterization of (±)-5,9α-dimethyl-2-[2-(4-fluorophenyl)ethyl]-2'-hydroxy-6,7-benzomor phan (fluorophen), a ligand suitable for visualization of opiate receptors in vivo

DOI: 10.1021/jm00365a017

Source and publish data:

Journal of Medicinal Chemistry p. 1643 - 1645 (1983)

Update date:2022-08-02

Topics:

Authors:

Rice Rice

Konicki Konicki

Quirion Quirion

Burke Jr.

Pert Pert

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Article abstract of DOI:10.1021/jm00365a017

A fluorinated derivative of the benzomorphan opiate agonist phenazocine, (±)-5,9α-dimethyl-2-[2-(4-fluorophenyl)ethyl-2'-hydroxy-6,7-benzomorphan (fluorophen), was prepared by N-acylation of (±)-5,9α-dimethyl-2'-hydroxybenzomorphan with (p-fluorophenyl)ac

Full text of DOI:10.1021/jm00365a017

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