Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (N- 1)-mer content through the use of trimeric phosphoramidite synthons

Article abstract of DOI:10.1080/15257779908043091

Use of fully protected trimeric phosphoramidite synthons in the synthesis of oligonucleotide phosphorothioate shows a substantial reduction (>85%) in (n-1)-mer content as compared to oligomers synthesized through coupling of standard phosphoramidite monom

Full text of DOI:10.1080/15257779908043091

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
Oligodeoxyribonucleotide Phosphorothioates:
Substantial Reduction of (N-1)-mer Content
Through the Use of Trimeric Phosphoramidite
Synthons
Alessandra Eleuteri , Daniel C. Capaldi , Douglas L. Cole & Vasulinga T.
Ravikumar
To cite this article: Alessandra Eleuteri , Daniel C. Capaldi , Douglas L. Cole & Vasulinga T.
Ravikumar (1999) Oligodeoxyribonucleotide Phosphorothioates: Substantial Reduction of
(N-1)-mer Content Through the Use of Trimeric Phosphoramidite Synthons, Nucleosides and
Nucleotides, 18:3, 475-483, DOI: 10.1080/15257779908043091
To link to this article: http://dx.doi.org/10.1080/15257779908043091
Published online: 04 Oct 2006.
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Date: 07 June 2016, At: 09:49