Inhibition of Renin by Angiotensinogen Peptide Fragmeents Containing the Hydroxy Amino Acid Residue 5-Amino-3-hydroxy-7-methyloctanoic Acid

DOI: 10.1021/jm00364a019

Source and publish data:

Journal of Medicinal Chemistry p. 1457 - 1462 (1983)

Update date:2022-08-05

Topics:

Authors:

Johnson, Rodney L.

Verschoor, Karen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00364a019

The 3R,5S and 3S,5S diastereoisomers of the hydroxy amino acid 5-amino-3-hydroxy-7-methyloctanoic acid (AHMOA) were synthesized from L-leucine and then incorporated into various peptide fragments of angiotensinogen to give the following polypeptides: AHMO

Full text of DOI:10.1021/jm00364a019

Products guided by the article

Product name:N^α-Boc-N^?-Bom-His-Leu-Leu-Val-Phe-OMe

Cas No:86835-09-8

R&D Labs maybe for 86835-09-8

Nanjing Chemzam Pharmtech Co., Ltd.

Contact:+86-25-86462165,+86-13915979898

Address:C5-1，6 Maiyue Road，Maigaoqiao，Nanjing，Jiangsu，China
Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
Shandong Yaroma Perfumery Co., Ltd.

Contact:+86- 531- 88024598

Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.

website:http://www.sino-strong.com.cn

Contact:+86-28-82666753

Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China

Relevant to this article

THE PHILICITY OF A TRIPLET CARBENE: ADDITIONS OF DIPHENYLCARBENE TO STYRENE SUBSTRATES

Doi:10.1016/S0040-4039(01)91299-7
(1984)
Piperazine as a linker for incorporating the nitric oxide-releasing diazeniumdiolate group into other biomedically relevant functional molecules

Doi:10.1021/jo9901539
(1999)
Hydrogenation of benzonitrile to benzylamine catalyzed by ruthenium hydride complexes with P-NH-NH-P tetradentate ligands: Evidence for a hydridic-protonic outer sphere mechanism

Doi:10.1021/om700783e
(2007)
Semisynthesis of labdane diterpene metabolites from the nudibranch Pleurobranchaea meckelii

Doi:10.1016/j.tet.2007.09.039
(2007)
Synthesis and characterization of homoannularly disubstituted and heteroannularly trisubstituted ferrocene derivatives by arsenic and silicon or by arsenic and tin

Doi:10.1021/om7004468
(2007)
Doi:10.1021/ja00870a018
(1962)

Article Doi