Synthesis and Substituent Effects on Antibacterial Activity, Alkaline Hydrolysis Rates, and Infrared Absorption Frequencies of Some Cephem Analogues Related to Latamoxef (Moxalactam)

DOI: 10.1021/jm00365a006

Source and publish data:

Journal of Medicinal Chemistry p. 1577 - 1582 (1983)

Update date:2022-08-05

Topics: Synthesis IR spectroscopy Spectrophotometry Minimum inhibitory concentration (MIC) Substituent Effects Structure-Activity Relationship (SAR) Alkaline Hydrolysis Cephem Hydrolysis kinetics Chromatography (HPLC/TLC) β-Lactam Ring

Authors:

Narisada, Masayuki

Yoshida, Tadashi

Ohtani, Mitsuaki

Ezumi, Kiyoshi

Takasuka, Mamoru

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00365a006

Relationships between intrinsic antibacterial activity and β-lactam reactivity of 7β-<(4-hydroxyphenyl)acetyl>amino- and 7β-<(4-hydroxyphenyl)malonyl>amino derivatives of 1-oxa- and 1-thiacephems, with or without the 7α-methoxy group (1-8), were investiga

Full text of DOI:10.1021/jm00365a006

Products guided by the article

Product name:(6R,7R)-7-{2-(4-Methoxy-benzyloxycarbonyl)-2-[4-(4-methoxy-benzyloxy)-phenyl]-acetylamino}-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

Cas No:86862-94-4

R&D Labs maybe for 86862-94-4

Jinan Decheng Hemu Medical Technology Co.，Ltd.

Contact:+86-531-68650525

Address:NO.554 Zhengfeng Road High-new Technology Development Zone
wansheng

Contact:86-0311-88310000

Address:Room 1109 Sunshine Plaza,No.46 Tang Gudun Road,Jianghan District Wuhan Hubei
Sichuan Mianzhu Ronghong Chemical Co.,LTd

Contact:8613981840544

Address:XINSHI INDUSTRY PARK,MIANZHU,SICHUAN,CHINA
Changzhou naidechemical Co.Ltd

Contact:+86-519-82589807

Address:NO.25,Houyang street,Jintan,Changzhou City
Hangzhou Sartort Biopharma Co., Ltd

website:http://www.sartort.com

Contact:86-571-87039693

Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China

Relevant to this article

Reactivity of CpCo 16e half-sandwich complexes containing a chelating 1,2-dicarba-closo-dodecaborane-1,2-dichalcogenolate ligand toward phenylacetylene

Doi:10.1021/om700454p
(2007)
Organoethynylxenon(II) tetrafluoroborates, [RC≡CXe][BF₄] - The first examples of isolated alkynylxenonium salts: Preparation and multi-NMR characterisation

Doi:10.1002/ejic.200600366
(2006)
An approach to the synthesis of the naphthyridinomycin alkaloids the synthesis of two subunits

Doi:10.1016/S0040-4039(01)81394-0
(1984)
Doi:10.1021/ja01246a025
(1943)
Mechanistic studies of the allylic rearrangements of α-silyloxy allylic silanes to silyloxy vinylic silanes

Doi:10.1021/jo070634p
(2007)
PALLADIUM CATALYSED TANDEM CYCLISATION-ANION CAPTURE PROCESSES. HYDRIDE ION CAPTURE BY VINYLPALLADIUM SPECIES.

Doi:10.1016/S0040-4039(00)80488-8
(1988)

Article Doi