Addition of ethyl bromodifluoroacetate to lactones: Reactivity and stereoselectivity

DOI: 10.1055/s-2005-917113

Source and publish data:

Synlett p. 2627 - 2630 (2005)

Update date:2022-07-29

Topics: Catalysts Nucleophile Reaction Conditions Stereoselectivity Chelation Effects

Authors:

Cuenca, Ana B.

D'Hooge, Fran?ois

Gouge, Vanessa

Castelot-Deliencourt, Géraldine

Oulyadi, Hassan

Leclerc, Eric

Jubault, Philippe

Pannecoucke, Xavier

Quirion, Jean-Charles

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Article abstract of DOI:10.1055/s-2005-917113

Reformatsky-type additions, under various metal-mediated activation, of ethyl bromodifluoroacetate toward a series of unactivated lactones and various sugar lactones proceeded with medium to good yields and in a completely diastereoselective manner. Georg

Full text of DOI:10.1055/s-2005-917113

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