Synthesis and screening of bicyclic carbohydrate-based compounds: A novel type of antivirals

DOI: 10.1016/j.bmcl.2005.12.048

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1495 - 1498 (2006)

Update date:2022-08-03

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Authors:

Van Hoof, Steven

Ruttens, Bart

Hubrecht, Idzi

Smans, Gert

Blom, Petra

Sas, Benedikt

Van Hemel, Johan

Vandenkerckhove, Jan

Van Der Eycken, Johan

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Article abstract of DOI:10.1016/j.bmcl.2005.12.048

A small library of bicyclic carbohydrate derivatives was synthesized and screened. A strong and selective activity against cytomegalovirus was found. Structure-activity relationship for this new type of antivirals is discussed.

Full text of DOI:10.1016/j.bmcl.2005.12.048

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