Chemical and Pharmaceutical Bulletin p. 3024 - 3038 (1983)
Update date:2022-08-03
Topics:
Ishii
Ishikawa
Deushi
et al.
For the sake of establishment of a versatile synthetic method for benzo[c]phenanthridine alkaloids, improvement of the Robinson synthetic method was examined. Thirteen chalcones (7a-m) were prepared by condensation of two acetophenone derivatives (15 and 16) with eleven benzaldehyde derivatives (19a-k) as fundamental starting materials. Hydrocyanation of these chalcones (7a-1) except one (7m) gave the corresponding 2,4-bisaryl-4-oxobutyronitriles (8a-1). Eleven 2,4-bisaryl-4-oxobutyramides (9a-k) were also prepared.
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Doi:10.1021/bi00625a010
(1977)Doi:10.1080/15421400701503659
(2007)Doi:10.1021/jo00288a026
(1990)Doi:10.1039/b515636j
(2006)Doi:10.1002/chem.200600527
(2006)Doi:10.1007/BF00505954
(1984)
