Tetrahedron p. 5759 - 5772 (1999)
Update date:2022-08-04
Topics:
Seeberger, Peter H.
Caruthers, Marvin H.
Bankaitis-Davis, Danute
Beaton, Graham
A novel method for the efficient synthesis phosphorodithioate DNA using H-phosphonothioate synthons is described. The 5'-DMT-nucleotide H- phosphonothioate monomers were prepared in two high yielding steps, from commercially, available phosphoramidites. T
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