
Journal of the Chemical Society. Chemical communications p. 926 - 928 (1983)
Update date:2022-08-05
Topics:
Martin, Olivier R.
Szarek, Walter A.
The synthesis of an N-protected 2'-amino-2'-deoxy-1'-O-(2-deoxystreptamin-4-yl)-α-D-threo-D-gluco-octo-1',5':4',8'-dipyranose in nine steps from paromamine is described; the key steps are the conversion of paromamine into a protected octuronic acid derivative, followed by its 8',4'-lactonization upon removal of the O-protecting groups, and partial reduction of the resulting 'trans-decalone-like' lactone.
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(1983)