Tetrahedron p. 3337 - 3344 (1983)
Update date:2022-08-04
Topics:
Castro Dantas, T.N. de
Laval, J.P.
Lattes, A.
Functionalized phosphonium salts in Wittig reactions give ethylenic amines.With aldehydes the nature of the carbon chain and of the substituents on nitrogen have no influence on stereochemistry; ethylenic ketones, give aminopolyenes.Steroids give aminosteroids if a large excess of phosphonium salt is used.Amphiphilic compounds may therefore be prepared and aminoalkyl groups may be introduced to molecules with potential biological activities.
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(2006)Doi:10.1016/S0040-4039(00)94119-4
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(2006)
