Nucleosides, nucleotides and nucleic acids p. 1101 - 1104 (2005)
Update date:2022-09-26
Topics:
Hrdlicka, Patrick J.
Kumar, T. Santhosh
Wengel, Jesper
A convergent route to 2′-amino-α-L-LNA-T phosphoramidite building block 16 has been developed. Key steps include 1) introduction of a C2-azido group prior to nucleobase-coupling, 2) tandem Staudinger and intramolecular nucleophilic substitution reaction,
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