Helvetica Chimica Acta p. 2769 - 2777 (1983)
Update date:2022-08-03
Topics:
Kvita, Vratislav
Sauter, Hanspeter
Rihs, Grete
The nucleophilic attack of substituted anilines at position 6 of methyl coumalate (1) opens the α-pyrone ring to form 4-arylamino-3-(methoxycarbonyl)butadien-1-carboxylic acid 2 (Scheme 1).The latter are easily decarboxylated at room temperature in polar
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