A novel method for the synthesis of 9-[[2-hydroxy-1-(aminomethyl)ethoxy]methyl]guanine. A potential antiviral agent

DOI: 10.1016/S0040-4039(00)99952-0

Source and publish data:

Tetrahedron Letters p. 613 - 616 (1984)

Update date:2022-09-26

Topics: Synthesis Chemical reactions Hydroxy Experimental method Antiviral agent Aminomethyl Ethoxy

Authors:

Liu Liu

Kuzmich Kuzmich

Lin Lin

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Article abstract of DOI:10.1016/S0040-4039(00)99952-0

9-[[2-Hydroxy-1-(aminomethyl)ethoxy]methyl]guanine (1a), an amino analogue of 9-[[2-hydroxy-1-(hydroxymethyl)-ethoxy]methyl]guanine (I) which is a potent antiviral agent, has been synthesized via a multistep-synthesis.

Full text of DOI:10.1016/S0040-4039(00)99952-0

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