Building complex glycopeptides: Development of a cysteine-free native chemical ligation protocol

Article abstract of DOI:10.1002/anie.200600538

(Figure Presented) The missing link: Reiterative ligations based on non-cysteine and cysteine-based acyl acceptors have been used to prepare synthetic polypeptides and proteins with multiple sites of glycosylation. Highly complex positionally defined glyc