Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity

DOI: 10.1021/jm0602662

Source and publish data:

Journal of Medicinal Chemistry p. 4946 - 4952 (2006)

Update date:2022-08-02

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Authors:

Biava, Mariangela

Porretta, Giulio Cesare

Poce, Giovanna

Supino, Sibilla

Deidda, Delia

Pompei, Raffaello

Molicotti, Paola

Manetti, Fabrizio

Botta, Maurizio

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Article abstract of DOI:10.1021/jm0602662

On the basis of suggestions derived either from a pharmacophoric model for antitubercular agents or from a structure-activity relationship analysis of many pyrroles previously described by us, we report here the design and synthesis of new analogues of 1,

Full text of DOI:10.1021/jm0602662

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