An Efficient Biocatalyzed Kinetic Resolution of Methyl (Z)-3-Arylsulphinylpropenoates

DOI: 10.1016/S0040-4039(00)60749-9

Source and publish data:

Tetrahedron Letters p. 4635 - 4638 (1994)

Update date:2022-07-30

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Authors:

Cardellichio, Cosimo

Naso, Francesco

Scilimati, Antonio

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Article abstract of DOI:10.1016/S0040-4039(00)60749-9

The enzymatic hydrolysis of racemic methyl (Z)- and (E)-3-arylsulphinylpropenoates by several microbial lipases and α-chymotrypsin (α-CHT) was studied.High enantioselectivity values (up to 99percent) were obtained using (Z)-methyl esters.

Full text of DOI:10.1016/S0040-4039(00)60749-9

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