Bioorganic and Medicinal Chemistry p. 1203 - 1207 (1996)
Update date:2022-08-03
Topics:
Gazit, Aviv
Chen, Jeffrey
Harald, App
McMahon, Gerald
Hirth, Peter
Chen, Irit
Levitzki, Alexander
Potent 4-anilido-substituted quinazolines which potently inhibit epidermal growth factor receptor (EGFR) kinase were prepared. Structure-activity relationship studies reveal high sensitivity to substitution at the aniline ring.
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