Chemistry Letters p. 71 - 72 (1999)
Update date:2022-08-02
Topics:
Kobayashi, Shu
Nagayama, Satoshi
Busujima, Tsuyoshi
Chiral copper(II)-catalyzed asymmetric aldol reactions of silyl enol ethers with aldehydes have been successfully carried out in a water-ethanol solution. The use of the protic solvent including water is essential in these reactions, and this report has proposed and demonstrated a new concept for solvents in catalytic asymmetric aldol reactions.
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