Journal of Medicinal Chemistry p. 253 - 256 (1985)
Update date:2022-08-06
Topics:
Tsushima, Tadahiko
Kawada, Kenji
Tsuji, Teruji
Tawara, Katsuya
Both threo and erythro 1-fluorodehydroxylated chloramphenicol analogues were synthesized and tested for antimicrobial activity.None showed antibacterial or antifungal activity, clearly demonstrating that substitution of the secondary hydroxyl group with f
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