Fluorine-Containing Amino Acids and Their Derivatives. 4. Synthesis and Antibacterial Activity of Threo and Erythro 1-Fluorodehydroxylated Chloramphenicol Analogues

DOI: 10.1021/jm00380a019

Source and publish data:

Journal of Medicinal Chemistry p. 253 - 256 (1985)

Update date:2022-08-06

Topics:

Authors:

Tsushima, Tadahiko

Kawada, Kenji

Tsuji, Teruji

Tawara, Katsuya

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00380a019

Both threo and erythro 1-fluorodehydroxylated chloramphenicol analogues were synthesized and tested for antimicrobial activity.None showed antibacterial or antifungal activity, clearly demonstrating that substitution of the secondary hydroxyl group with f

Full text of DOI:10.1021/jm00380a019

Products guided by the article

Product name:N-[1-(tert-Butyl-dimethyl-silanyloxymethyl)-2-fluoro-2-(4-nitro-phenyl)-ethyl]-2,2-dichloro-acetamide

Cas No:93863-38-8

R&D Labs maybe for 93863-38-8

Beijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)

Contact:010-52876516

Address:tongzhoubeiyuan
Hebei Tete Trade Co., Ltd.

Contact:86-311-83160559

Address:shijiazhuang
Rugao Jinling Chemical Co., Ltd.(expird)

Contact:0086-513-68005586

Address:Lianluo new village huangshi town Rugao city Jiangsu Province.
HangZhou Yaos COOP IMP.&EXP CO. LTD

website:http://www.yaoschem.com

Contact:13606507143

Address:Building 4, ZiJin Qizhen Building, No.859 West ShiXiang Rd., SanDun Town, XiHu District
Guangzhou Chemical Reagent Factory

Contact:+86-20-8435 9820 or 8435 7345

Address:Southern Guangzhou, Guangdong, China

Relevant to this article

Doi:10.1021/ja00876a043
(1962)
Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions

Doi:10.1021/ja055886r
(2006)
A new modular and flexible approach to [1,2,3]triazolo[1,5-a][1,4]benzodiazepines

Doi:10.1016/j.tetlet.2007.03.121
(2007)
Sustainable synthesis of 1,2,3,4-cyclohexanetetracarboxylate from sugar-derived carboxylic acids

Doi:10.1039/d0cc02163f
(2020)
Synthesis of (-)-homogalanthamine from naltrexone

Doi:10.1021/jo1022487
(2011)
Zirconocene dichloride catalyzed hydrodefluorination of C sp 2-F bonds

Doi:10.1002/anie.201207036
(2012)

Article Doi