
Tetrahedron Letters p. 2675 - 2678 (1998)
Update date:2022-08-02
Topics:
Williams, David R.
Cortez, Guillermo S.
A concise enantiocontrolled synthesis of the enamine-aminal heterocyclic core found in the zoanthamine alkaloids is presented. Conjugate addition of a chiral imine provides for excellent diastereofacial selectivity in the generation of the quaternary C9 asymmetry of 4.
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