INTRAMOLECULAR FREE RADICAL CYCLISATIONS ONTO VINYL ETHERS. A METHOD FOR THE SYNTHESIS OF β-OXY-γ-BUTYROLACTONES

DOI: 10.1016/S0040-4039(01)81427-1

Source and publish data:

Tetrahedron Letters p. 4317 - 4320 (1984)

Update date:2022-08-04

Topics:

Authors:

Ladlow, Mark

Pattenden, Gerald

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)81427-1

Radical cyclisation of the vinyl ether bromides (2) and (7) in the presence of tri-n-butylstannane produces precursors to the β-oxy-γ-butyrolactones (6) and (9) in high yields (>80percent).By contrast, treatment of (2) and (7) with bis-(dimethylglyoximato)(pyridine)cobalt(I) chloride followed by oxidation of the intermediates (5) and (11) led to the corresponding unsaturated β-oxy-γ-butyrolactones (4) and (12) respectively.

Full text of DOI:10.1016/S0040-4039(01)81427-1

Products guided by the article

Product name:2-Cyclohexen-1-ol, 2-(2-methylpropoxy)-

Cas No:94532-19-1

R&D Labs maybe for 94532-19-1

ChengduChroma-BiotechCo.,Ltd.

Contact:86-28-61993785

Address:No.70-13-21, North Section, Erhuan
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China
Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)
Shao Xing Empire Import&Export CO.,ltd

Contact:86-575-82127757

Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China

Relevant to this article

A new class of anti-thrombosis hexahydropyrazino-[1′,2′:1,6]pyrido-[3,4-b]-indole-1,4-dions: Design, synthesis, log K determination, and QSAR analysis

Doi:10.1016/j.bmc.2007.06.012
(2007)
Total synthesis of aculeatins A and B via a tethered oxa-Michael approach

Doi:10.1016/j.tetlet.2007.05.026
(2007)
Asymmetric meso-aziridine ring-opening reactions using a chiral zirconium catalyst

Doi:10.1039/b914271c
(2009)
Synthesis and single crystal X-ray structure of ethyl 2-(1,3-benzoxazol-2- yl)-5-oxo-3-(4-toluidino)-2,5-dihydro-4-isoxazolecarboxylate

Doi:10.1515/znb-2007-0513
(2007)
A red Cy3-based biarsenical fluorescent probe targeted to a complementary binding peptide

Doi:10.1021/ja070003c
(2007)
Synthesis and biological evaluation of N-pyrazolyl-N′-alkyl/benzyl/ phenylureas: A new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis

Doi:10.1021/jm0704402
(2007)

Article Doi