SYNTHESIS OF MYO-INOSITOL 1,4,5-TRISPHOSPHATE 3-PHOSPHOROTHIOATE AS AN INHIBITOR OF MYO-INOSITOL 1,3,4,5-TETRAKISPHOSPHATE 3-PHOSPHATASE

DOI: 10.1016/S0040-4039(00)76770-0

Source and publish data:

Tetrahedron Letters p. 1605 - 1608 (1994)

Update date:2022-08-03

Topics:

Authors:

Liu, Changsheng

Potter, Barry V. L.

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Article abstract of DOI:10.1016/S0040-4039(00)76770-0

The synthesis of racemic myo-inositol 1,4,5-triphosphate 3-phosphorothioate from myo-inositol is described using a protection/deprotection sequence employing allyl, benzyl and p-methoxybenzyl groups to facilitate selective 3-position thiophosphorylation.

Full text of DOI:10.1016/S0040-4039(00)76770-0

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