STEREOSPECIFIC SYNTHESIS OF (25R)-26-HYDROXYCHOLESTEROL VIA SIGMATROPIC REARRANGEMENT. A NEW STEREOSELECTIVE TWO-CARBON HOMOLOGATION OF 20-KETO STEROIDS TO THE 23-ALDEHYDE.

DOI: 10.1016/S0040-4039(01)80842-X

Source and publish data:

Tetrahedron Letters p. 5021 - 5024 (1985)

Update date:2022-08-03

Topics:

Authors:

Midland, M. Mark

Kwon, Young C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)80842-X

Pregnenolone was stereoselectively converted into (25R)-26-hydroxycholesterol using a stereoselective hydroboration, assymetric reduction and a strereospecific <2.3> sigmatropic rearrangement as key steps.

Full text of DOI:10.1016/S0040-4039(01)80842-X

Products guided by the article

Product name:(25R)-cholest-5-ene-3β,26-diol

Cas No:96553-74-1

R&D Labs maybe for 96553-74-1

Jiangsu Seed Chem Co.,Ltd.

Contact:86-513-84128750/13773795976

Address:No.48.Youyi West Road ,Rudong Development Zone,Jiangsu Province,China
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
JIEJIE GROUP CO.,LTD.

Contact:+86 021-51698675

Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China

Relevant to this article

Asymmetric total synthesis and formal total synthesis of the antitumor sesquiterpenoid (+)-eremantholide A

Doi:10.1021/ol0700862
(2007)
REDUCTION OF β-HYDROXYSULFOXIDES: APPLICATION TO THE SYNTHESIS OF OPTICALLY ACTIVE EPOXIDES

Doi:10.1016/S0040-4039(00)61904-4
(1985)
A NOVEL CYCLIZATION REACTION OF OXIDODIAZOALKANES: FORMATION OF PYRAZOLES AND PYRIDAZINES

Doi:10.1016/S0040-4039(00)89171-6
(1985)
Possible role of the carbohydrate residues on the structure of the N-terminus of glycophorin AM.

Doi:10.1016/S0008-6215(00)90301-X
(1986)
Lithium 2-Lithio-1,1,3,3-tetraphenylpropenide

Doi:10.1039/c39850000012
(1985)
IRIDOIDS : ON THE SYNTHESIS AND STRUCTURE OF SPECIONIN

Doi:10.1016/S0040-4039(01)80819-4
(1985)

Article Doi