Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

DOI: 10.1021/jm00146a014

Source and publish data:

Journal of Medicinal Chemistry p. 1062 - 1066 (1985)

Update date:2022-08-04

Topics:

Authors:

Almquist

Jennings-White

Chao Chao

Steeger Steeger

Wheeler Wheeler

Rogers Rogers

Mitoma Mitoma

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00146a014

Two pentapeptide analogues (14 and 15) of the ketomethylene-containing angiotensin converting enzyme (ACE) inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline (1) were synthesized and evaluated as ACE inhibitors and antihypertensive agents. Compound

Full text of DOI:10.1021/jm00146a014

Products guided by the article

Product name:N^ε-(benzyloxycarbonyl)-N^α-(cyclobutylcarbonyl)-L-lysine methyl ester

Cas No:96867-09-3

R&D Labs maybe for 96867-09-3

Shanghai united Scientific Co.,Ltd.

Contact:+86-21-53535353

Address:28F No.900 huaihai Road Shanghai China
Hangzhou Kai Peng Biotechnology Co., Ltd.

Contact:86-571-89939007

Address:NO. 499, Wensan West Road, Xihu District, Hangzhou, 310012, China
Molobelamltrading

Contact:27-792-602929

Address:SIDNEY MUFAMADI STREET 009949 X44 0700 POLOKWANE,LIMPOPO
Guangzhou Puho Pharmaceutical Technology Co. Ltd.

Contact:86-20-29848035/29848075

Address:No.166, Chaoyang East Road, Panyu District, Guangzhou City, Guangdong Province
zhengzhou Triz Pharma-Tech Co., Ltd

website:http://www.Trizpharma-tech.com

Contact:+86-0371-86597269，53392065

Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street

Relevant to this article

Synthesis of methylated quercetin analogues for enhancement of radical-scavenging activity

Doi:10.1039/C7RA02329D
(2017)
Doi:10.1016/0040-4020(84)85082-6
(1984)
A New Synthesis of (+/-)-Frullanolide: Application of 2-Phenylselenopropanoic Acid

Doi:10.1055/s-1985-31092
(1985)
Expanding the scope of donor/acceptor carbenes to N -phthalimido donor groups: Diastereoselective synthesis of 1-cyclopropane α-amino acids

Doi:10.1021/ol3029127
(2012)
Doi:10.1021/jo01061a003
(1961)
NITRATION SUBSTITUTED STYRENES WITH NITRYL IODIDE

Doi:10.1016/S0040-4039(00)98431-4
(1985)

Article Doi