Synthesis and biological activity of pentapeptide analogues of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

DOI: 10.1021/jm00146a014

Source and publish data:

Journal of Medicinal Chemistry p. 1062 - 1066 (1985)

Update date:2022-08-04

Topics:

Authors:

Almquist

Jennings-White

Chao Chao

Steeger Steeger

Wheeler Wheeler

Rogers Rogers

Mitoma Mitoma

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00146a014

Two pentapeptide analogues (14 and 15) of the ketomethylene-containing angiotensin converting enzyme (ACE) inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline (1) were synthesized and evaluated as ACE inhibitors and antihypertensive agents. Compound

Full text of DOI:10.1021/jm00146a014

Products guided by the article

Product name:N^ε-(benzyloxycarbonyl)-N^α-(cyclobutylcarbonyl)-L-lysine methyl ester

Cas No:96867-09-3

R&D Labs maybe for 96867-09-3

NEM CHEMICAL CO.，LTD

website:http://www.NEM.COM.CN

Contact:+86-393-4411771

Address:The west section of shengli Road,Puyang,Henan Province,China
Guangzhou Reachin Chemical Co., Ltd

Contact:+86-20-37087379 ext.604

Address:A122C-1, Tianyuan Plaza, 401 Tianyuan Rd., Tianhe, Guangzhou, China
Jinan Kaypharm Chemical Co.,Ltd

Contact:86-0531-86986780

Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

Synthesis of methylated quercetin analogues for enhancement of radical-scavenging activity

Doi:10.1039/C7RA02329D
(2017)
Doi:10.1016/0040-4020(84)85082-6
(1984)
A New Synthesis of (+/-)-Frullanolide: Application of 2-Phenylselenopropanoic Acid

Doi:10.1055/s-1985-31092
(1985)
Expanding the scope of donor/acceptor carbenes to N -phthalimido donor groups: Diastereoselective synthesis of 1-cyclopropane α-amino acids

Doi:10.1021/ol3029127
(2012)
Doi:10.1021/jo01061a003
(1961)
NITRATION SUBSTITUTED STYRENES WITH NITRYL IODIDE

Doi:10.1016/S0040-4039(00)98431-4
(1985)

Article Doi