PALLADIUM-CATALYZED CYCLIZATION REACTIONS OF 3-PROPARGYLTHIO-1,2,4-TRIAZIN-5(2H)-ONES TO THIAZOLO-1,2,4-TRIAZINONES

Article abstract of DOI:10.1016/S0040-4039(00)98442-9

Selective transformation of 3-propargylthio-1,2,4-triazin-5(2H)-ones (1) to 6-methylene-6,7-dihydro-4H-thiazolo<2,3-c><1,2,4>- triazin-4-ones (2) and 3-methylene-2,3-dihydro-7H-thiazolo<3,2-b><1,2,4>triazin-7-ones (3) is performed under the conditions of Pd(II) salt or sodium hydroxide catalysis, respectively.