Asymmetric Synthesis of the C-1-C-8 Fragment of Leukotriene B4 and C-11-C-20 Fragments of Leukotriene B4 and 12(S)-Hydroxy-5,8,14(Z), 10(E) Eicosatetraenoic Acid

Article abstract of DOI:10.1016/S0957-4166(00)82171-0

An asymmetric synthesis of the C-1-C-8 fragment of LTB₄ based on the reduction of optically active β-ketosulfoxides is described as well as the asymmetric synthesis of the C-11-C-20 fragments of LTB₄ and 12(S)-hydroxy-5,8,14(Z), 10(E