Journal of Medicinal Chemistry p. 1447 - 1453 (1985)
Update date:2022-08-04
Topics: Synthesis Substituted β-Lactam Biological Activity Experimental Antibiotics
Woulfe, Steven R.
Miller, Marvin J.
The synthesis of substituted <<3(S)-(acylamino)-2-oxo-1-azetidinyl>oxy>acetic acids (1) is described. 3-<(Carbobenzyloxy)amino>-N-hydroxy-2-azetidinones (13a, b), prepared from serine and threonine, were alkylated with 2-(trimethylsilyl)ethyl bromoacetate
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