AN EFFICIENT SYNTHESIS OF A KEY INTERMEDIATE FOR OPTICALLY ACTIVE 5,6-CIS-CARBAPENEM ANTIBIOTICS

DOI: 10.1016/S0040-4039(00)83870-8

Source and publish data:

Tetrahedron Letters p. 3749 - 3752 (1986)

Update date:2022-08-05

Topics:

Authors:

Tamura, Norikazu

Kawano, Yasuhiko

Matsushita, Yoshihiro

Yoshioka, Kouichi

Ochiai, Michihiko

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Article abstract of DOI:10.1016/S0040-4039(00)83870-8

A versatile intermediate (18) for optically active 5,6-cis-carbapenem antibiotics was synthesized with a highly regioselective intramolecular aldol condensation as a key step.

Full text of DOI:10.1016/S0040-4039(00)83870-8

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