SYNTHESIS OF METHYL 3-DEOXY-3-METHYLAMINOARABINOPYRANOSIDE, A COMPONENT OF SOME AMINOGLYCOSIDE ANTIBIOTICS

Article abstract of DOI:10.1016/S0040-4020(01)96517-2

Amino sugar 1 has been synthesized in racemic form as a mixture of anomers from sorbic aldehyde.An intramolecular N-sulfinyl dienophile Diels-Alder strategy was used to stereospecifically generate the chiral centers of pentose 1.