Journal of Organic Chemistry p. 167 - 174 (1986)
Update date:2022-07-29
Topics:
Lin, Jyh-Ming
Koch, Kevin
Fowler, Frank W.
N-Acyl imines, produced by the flash vacuum thermolysis of hydroxamic acid derivatives, participate in the intramolecular ene reaction to give nitrogen heterocycles.The reaction is accelerated by carboxyl substituents on the carbon atom of the N-acyl imine, and the reaction is more succesful for the production of pyrrolidine rather than piperidine derivatives.
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