Journal of the Chemical Society. Perkin transactions II p. 337 - 340 (1984)
Update date:2022-08-11
Topics:
Temerk, Yassien M.
Kamal, Mostafa M.
Ahmed, Mohamed E.
The rates of hydrolysis of a series of substituted benzylidenesalicylohydrazide derivatives 40percent (v/v) ethanol-buffer mixture have been investigated by differential pulse polarography.The hydrolysis is catalysed by H+ and its rate follows strictly first-order kinetics.The rate constant decreases with increasing pH up to around pH 3.9, beyond which no measurable reaction was observed; here the protonation of imine begins to be significantly incomplete.The attack of water on the protonated substrate is considered to be the rate-determining step.The effects of pH, molecular structure, and temperature on the reaction rate and the activation energy are reported.Thermodynamic parameters (ΔG(formula), ΔH(formula), and ΔS(fomula)) for the hydrolysis are discussed.
View MoreHangzhou Dingyan Chem Co., Ltd
website:http://www.dingyanchem.com
Contact:86-571-87157530
Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
Anhui Biochem United Pharmaceutical Co., Ltd.
Contact:0086 551 5167062 / 5228268
Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
Chengdu CSH Pharmaceutical Co.,ltd
Contact:+86-(28)-85321971
Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Zhejiang kehong chemical co., ltd
Contact:0086-575-85522000
Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
chengdu firsterchem Pharmaceutical Co., Ltd.
Contact:028-66825849
Address:chengdu
Doi:10.1016/S0040-4039(98)00622-4
(1998)Doi:10.1039/c5ra23251a
(2016)Doi:10.1021/ja01031a044
(1969)Doi:10.1021/j100175a095
(1991)Doi:10.1039/P19810001433
(1981)Doi:10.1039/c5cc02472b
(2015)
