835-64-3Relevant articles and documents
A two-photon ESIPT based fluorescence probe for specific detection of hypochlorite
Chen, Liyan,Park, Sang Jun,Wu, Di,Kim, Hwan Myung,Yoon, Juyoung
, p. 526 - 532 (2018)
Hypochlorous acid (HOCl) is one important member of reactive oxygen species (ROS) familyresponsible for various human diseases. Although many contributions have been made to develop fluorescent probes for sensing HOCl, many of them suffer small Stokes shifts, sophisticated synthetic procedure, and slow reaction rate. In the current study, we designed and synthesized an ESIPT based fluorescence probe with diaminomeleonitrile (DMN) as reactive site. The probe can detect HOCl with high selectivity and sensitivity. It also has large Stokes shift and rapid reaction rate. Moreover, it can be utilized to monitor exogenous and endogenous HOCl in living cells and tissues via two-photon microscopy.
Heterogeneous palladium (II)-complexed dendronized polymer: A rare palladium catalyst for the one-pot synthesis of 2-arylbenzoxazoles
George, Smitha,Sreekumar, Krishnapillai
, (2020/12/14)
The palladium complex of dendronized amine polymer (EG–Gn–Pd, n = 0, 1 and 2) having ethylene glycol-initiated polyepichlorohydrin as core was synthesized on a Merrifield resin support and was well characterized. Generally, palladium catalysts are known for carbon–carbon coupling reactions. Here, a developed catalyst was found to be good for benzoxazole synthesis. Higher generation dendronized polymer (EG–G2–Pd) was found to be better catalyst over lower generation dendronized polymers. Moreover, dendronized polymers were found to be a better catalyst over dendrigraft polymers. The catalyst reusability was checked and good yield was obtained for five cycles.
Synthesis and X-ray crystal structures of three new nickel(II) complexes of benzoylhydrazones: Catalytic applications in the synthesis of 2-arylbenzoxazoles
Layek, Samaresh,Agrahari, Bhumika,Kumar, Akash,Dege, Necmi,Pathak, Devendra D.
, (2019/11/11)
Three new complexes of nickel(II), having general formula [Ni(L1)(PPh3)] (1), [Ni(L1)(4-picoline)] (2), and [Ni(L2)(4-picoline)] (3) were synthesized by the reaction of Ni(OAc)2·4H2O with corresponding benzolyhydrazine-derived Schiff base ligands i.e. [4-(diethylamino)-2-hydroxybenzylidene]-benzohydrazonic acid (H2L1) or [2-(hydroxynaphthalen-1-yl)methylene]-benzohydrazonic acid (H2L2) and PPh3/4-picoline as co-ligand in 1:1:1 ratio in methanol. All the three complexes were air-stable, isolated as reddish brown solids and characterized by Elemental analysis, FT-IR, 1H, 13C{1H}, 31P{1H} NMR spectroscopy and mass spectrometry. The structures of all three complexes were determined by single crystal X-ray diffraction studies which revealed the distorted square planar geometry of the complexes. In these complexes, three coordination sites were occupied by ONO pincer type Schiff base ligand and the fourth site was blocked by phosphorus (P) or nitrogen (N) atom of the co-ligand. The catalytic potential of all three complexes was explored in the synthesis of a series of 2-arylbenzoxazoles from aldehydes and 2-aminophenol, using low catalyst loading (0.5 mol%). Complex 1 was found to be the best catalyst among three complexes, for the synthesis of a series of 2-aryl benzoxazoles. The ease of synthesis, air-stability and robustness of the catalyst, and good TONs are some of the key characteristics of the described catalytic system.
Sulfur-Promoted Synthesis of Benzoxazoles from 2-Aminophenols and Aldehydes
Nguyen, Le Anh,Dang, Thai Duy,Ngo, Quoc Anh,Nguyen, Thanh Binh
supporting information, p. 3818 - 3821 (2020/06/10)
Elemental sulfur (S8) was found to be an excellent stoichiometric oxidant to promote oxidative condensation of 2-aminophenols with a wide range of aldehydes, including aliphatic aldehyde such as cyclohexanecarboxaldehyde. The reactions were catalyzed by sodium sulfide in the presence of DMSO as an additive. The benzoxazole products were obtained in satisfactory yields. The reaction conditions could be applied to larger syntheses (10–50 mmol).
