129748-28-3

Basic information

• Product Name: 1,1,5-trimethylfuro[3,4-c]pyridine-3,4(1H,5H)-dione
• Synonyms: 1,1,5-Trimethylfuro[3,4-c]pyridine-3,4(1H,5H)-dione
• CAS NO: 129748-28-3
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.1992
• Mol File: 129748-28-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 475°C at 760 mmHg
• Flash Point: 241.1°C
• Density: 1.28g/cm³
• Vapor Pressure: 3.46E-09mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: 1,1,5-trimethylfuro[3,4-c]pyridine-3,4(1H,5H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,5-trimethylfuro[3,4-c]pyridine-3,4(1H,5H)-dione(129748-28-3)
• EPA Substance Registry System: 1,1,5-trimethylfuro[3,4-c]pyridine-3,4(1H,5H)-dione(129748-28-3)

Safety Data

• Hazardous Substances Data: 129748-28-3(Hazardous Substances Data)

Usage

Chemical compound

A substance formed by a chemical reaction and consisting of a single type of molecule.

Complex molecular structure

The compound has a complex arrangement of atoms and bonds.

Heterocycle

A type of organic compound that contains a ring of atoms with at least one atom being different from carbon.

Furan ring

A heterocyclic compound consisting of a five-membered ring with four carbon atoms and one oxygen atom.

Pyridine ring

A heterocyclic compound consisting of a six-membered ring with alternating carbon and nitrogen atoms.

Pharmaceutical research

The compound is used in the study and development of drugs and medications.

Medicinal agent

The compound has potential for use in the treatment of various diseases.

Unique structure and properties

The compound has a distinct arrangement of atoms and bonds that give it specific characteristics.

Treatment of diseases

The compound has been studied for its potential use in treating various diseases, although further research is needed.

Organic chemistry

The field of chemistry that deals with the study of carbon-containing compounds and their reactions.

Further research needed

More studies are required to fully understand the compound's potential applications and effects.

Upstream product

• 80-48-8 methyl p-toluene sulfonate 
• 155887-48-2 1,1-Dimethyl-6,7-dihydro-1H,5H-furo[3,4-c]pyridine-3,4-dione 
• 1379803-83-4 ethyl 4-((E)-2-(dimethylamino)vinyl)-2,5-dihydro-5,5-dimethyl-2-oxofuran-3-carboxylate 
• 74-89-5 methylamine 
• 290-87-9 1,3,5-Triazine 
• 115-22-0 3-Hydroxy-3-methyl-2-butanone 
• 105-53-3 diethyl malonate 
• 74-88-4 methyl iodide 
• 34494-98-9 4,5,5-trimethyl-2-oxo-2,5-dihydrofuran-3-carboxylic acid N-methylamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 144084-35-5 N-tert-butyl-2-methoxynicotinamide 
• 144084-34-4 2-chloro-3-(N-tert-butylcarbamoyl)pyridine 
• 2942-59-8 2-chloronicotinic acid 
• 49609-84-9 2-Chloronicotinoyl chloride 

Relevant articles and documents

A three-step synthesis of cerpegin

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One-pot three steps synthesis of cerpegin

Cerpegin 1 was synthesized in a one-pot reaction at room temperature catalysed by cesium carbonate with an overall of 75% yield. 3-Hydroxy-3-methyl-2-butanone 2 reacted with diethyl malonate 3 to give 2-ethoxycarbonyl-3,4,4-trimethyl-2-buten-4-olide 4. Then 4 with s-triazine gave to 1,1-dimethylfuro[3,4-c]pyridine-3,4(1H, 5H)-dione 5 and which was alkylated with methyliodide to cerpegin.

Synthesis and hydrolysis of bicyclic 2-Imino-2,5-dihydrofurans fused to a pyridine ring

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Two versatile routes towards Cerpegin and analogues: Applications of a one pot reaction to new analogues of Cerpegin

Simple and efficient routes to the natural alkaloid Cerpegin and new analogues are described herein. In a first approach, we extend the scope of a one pot three steps reaction, which permits the synthesis of new analogues of Cerpegin, substituted in different ways. In a second line of approach, we present an unprecedented synthesis of Cerpegin and analogues where methylfuranones are condensed with dimethylformamide diethylacetal (DMFDEA) to yield enaminolactone esters, which react easily with various primary amines affording Cerpegin and new analogues. We applied this second approach to the synthesis of new bis-Cerpegins and N-amino-Cerpegins. Most of the syntheses are performed under environmental friendly conditions.