Synthesis of a Cyclodextrin Heterodimer Having α- and β-Cyclodextrin Units and Its Cooperative and Site-Specific Binding

Article abstract of DOI:10.1246/cl.1994.167

A cyclodextrin heterodimer, which has α- and β-cyclodextrin units as two different receptor sites, was prepared.It showed cooperative and site-specific binding to isoamyl p-dimethylaminobenzoate with the alkyl group included in the β-cyclodextrin cavity while dimethylaminobenzene moiety partially included in the α-cyclodextrin cavity.This binding mode was substantiated by the fact that the TICT emission of this guest is greatly enhanced by the cyclodextrin heterodimer.