Tetrahedron p. 13641 - 13656 (1997)
Update date:2022-08-11
Topics:
Aoki, Kazumasa
Tomioka, Kiyoshi
Noguchi, Hiroshi
Koga, Kenji
Enantioselective deprotonation of 4-substituted cyclohexanones (1a-d) by chiral bidentate lithium amides ((R)-2a-j) having an alkyl- or a fluoroalkyl substituent at the amide nitrogen was examined. (R)-2i having a 2,2,2-trifluoroethyl group at the amide nitrogen was found to be an excellent chiral base for the present deprotonation reaction. Structures of (R)-2i in solution and solid state are discussed.
View MoreGuangzhou Chemical Reagent Factory
Contact:+86-20-8435 9820 or 8435 7345
Address:Southern Guangzhou, Guangdong, China
Shandong Yaroma Perfumery Co., Ltd.
Contact:+86- 531- 88024598
Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Wuxi Innopal International Trade CO.,LTD
Contact:+86-510-80711901-8003
Address:Room 402,Building 5,Longze Garden,No.17,South huanjiu Road,Yixing City, Jiangsu,China
Cangzhou Senary Chemical Science-tech Co., Ltd
Contact:+86-317-3563899, 3563699
Address:168 Jinde Road, Cangzhou, Hebei, China
SHOUGUANG BOYU CHEMICAL CO.,LTD
Contact:+86-536-8256719
Address:ROOM 1101&1103,BUILDING D,ZHONGTU MANSION,NO.6565 EAST FUSHOU STREET,WEIFANG CITY,SHANDONG,CHINA.
Doi:10.1021/acschemneuro.5b00248
(2016)Doi:10.1039/C8CC08250B
(2019)Doi:10.1016/S0040-4039(01)97853-0
(1970)Doi:10.1002/chem.201501683
(2015)Doi:10.1016/0020-1650(76)90004-0
(1976)Doi:10.1039/b100924i
(2001)